hrp0094p1-54 | Bone B | ESPE2021

Decreased bone mineral density in children receiving long-term anticoagulation is associated with pubertal development

Raimann Adalbert , Patsch Janina , Weber Michael , Haufler Florentina , Pees Christiane , Albinni Sulaima , Male Christoph , Haeusler Gabriele , Thom Katharina ,

Background: Children and adolescents with chronic conditions are at increased risk of secondary osteoporosis. In adult patients, long-term anticoagulation (LTA) including Vitamin K antagonist (VKA) treatment is associated with lower bone mineral density and hip fractures. In children and adolsescent, risk factors for impaired skeletal health and the role of LTA on bone metabolism during the vulnerable phase of linear bone growth remain poorly defined.<p cl...